The San Diego to Las Vegas road trip is a quintessential Southern California adventure that combines stunning desert landscapes, charming small towns, and vibrant city life. This San Diego to Las Vegas drive route allows you to experience the best of both worlds: the relaxed, beachy vibe of San Diego and the energetic, bustling atmosphere of Las Vegas.
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San Diego to Las Vegas Road Trip Itinerary โ Drive From San Diego to Las Vegas
Along the San Diego to Vegas road trip, youโll pass through breathtaking scenery, explore unique attractions, and discover hidden gems.
San Diego to Las Vegas Drive โ Distance and Route Overview
- Total Distance: Approximately 330 miles
- Estimated Driving Time: 5-6 hours (without stops)
Scenic Route to Take: For a more picturesque drive, consider taking Interstate 15 North, which passes through coastal views, rolling hills, and desert landscapes.

Drive from San Diego to Las Vegas โ First Itinerary
Letโs check out this San Diego to Las Vegas road trip itinerary, which covers natural attractions on the drive from San Diego to Las Vegas.
Day 1: San Diego to Palm Springs

- Distance: 140 miles
- Driving Time: ~2.5 hours
Palm Springs is a desert oasis known for its mid-century modern architecture, luxurious spas, and vibrant arts scene.
Things to Do:
- Palm Springs Aerial Tramway: Ride up to Mount San Jacinto for panoramic views of the Coachella Valley.
- Visit the Palm Springs Art Museum: Explore a diverse modern and contemporary art collection.
- Stroll Through Moorten Botanical Garden: Discover a unique desert plant collection and charming cactarium.
Overnight Stay: The Saguaro Palm Springs โ A colorful and trendy hotel offering a fun atmosphere and excellent amenities.
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Day 2: Palm Springs to Joshua Tree National Park

- Distance: 50 miles
- Driving Time: ~1 hour
Joshua Tree National Park is famed for its unique Joshua trees, rugged rock formations, and star-filled night skies.
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Things to Do:
- Hiking in Hidden Valley: Explore this scenic trail surrounded by impressive rock formations.
- Skull Rock: A must-see natural rock formation resembling a skull.
- Stargazing: Experience some of the best stargazing in Southern California.
Overnight Stay: Pioneertown Motel โ A rustic and charming motel with a Western-themed ambiance.
Day 3: Joshua Tree to Las Vegas
- Distance: 140 miles
- Driving Time: ~2.5 hours
Las Vegas is renowned for its dazzling entertainment, world-class dining, and iconic landmarks.

Things to Do:
- Explore The Strip: Visit famous hotels and casinos along Las Vegas Boulevard.
- Fremont Street Experience: Enjoy the vibrant nightlife and light shows in downtown Las Vegas.
- Red Rock Canyon: Take a short drive outside the city for stunning desert scenery and hiking opportunities.
Overnight Stay: The Venetian Resort โ A luxurious hotel featuring Italian-inspired architecture and a central location on The Strip.
San Diego to Las Vegas Road Trip โ Second Itinerary
This second itinerary for the San Diego to Las Vegas road trip will combine the best of Southern Californiaโs charming coastal towns with the allure of the Mojave Desert.

Scenic Route โ For the most picturesque drive, take the I-15 North. This route provides breathtaking views of the desert landscape, iconic Joshua trees, and stunning rock formations. It is also home to several notable stops that enhance the road trip experience.
Day 1: San Diego to Joshua Tree National Park
Distance: 160 miles, ~2.5 hours
Joshua Tree National Park is famous for its otherworldly landscapes, featuring rugged mountains, desert plains, and the unique Joshua trees. Itโs an excellent place for hiking, photography, and stargazing.

Things to Do:
- Hike the Hidden Valley Trail for stunning rock formations.
- Visit Keys View for panoramic views of the Coachella Valley.
- Explore Barker Dam, a historical site with petroglyphs and desert wildlife.
Overnight Stay: For an immersive experience, book a night at a charming desert lodge or campsite within the park.
Day 2: Joshua Tree to Calico Ghost Town
Distance: 100 miles, ~1.5 hours
Calico Ghost Town offers a glimpse into Californiaโs mining history. This preserved ghost town, once bustling during the silver mining boom, now serves as a historical park.

Things to Do:
- Tour the old mining tunnels.
- Explore the townโs shops and museum.
- Take a ride on the Calico & Odessa Railroad for scenic views of the area.
Overnight Stay: Stay in nearby Barstow at a comfortable motel or inn.
Day 3: Barstow to Las Vegas
Distance: 150 miles, ~2.5 hours
The final leg takes you to the vibrant city of Las Vegas, known for its entertainment, nightlife, and iconic Strip.

Things to Do:
- Walk the Las Vegas Strip to experience its famous casinos, themed hotels, and shows.
- Visit the Neon Museum to see vintage Vegas signs.
- Enjoy a scenic view from the High Roller, the worldโs tallest observation wheel.
Overnight Stay: For a central location, choose a mid-budget hotel on the Strip, such as the LINQ Hotel or Treasure Island.
Useful Tips โ San Diego to Vegas Road Trip

- Plan Fuel Stops: The desert stretches can be long without services, so fill your gas tank.
- Pack Essentials: Bring plenty of water, snacks, sunscreen, and a first-aid kit for the journey.
- Check Weather Conditions: Desert weather can be unpredictable; check forecasts to prepare for extreme heat or sudden storms.
- Book Accommodations in Advance: Especially during peak travel seasons, lodging can fill up quickly.
- Leave Early: Start early on this road trip to avoid the midday heat and maximize sightseeing time.
- Plan for Breaks: The desert heat can be intense, so plan regular stops to stretch and hydrate.
This San Diego to Las Vegas road trip perfectly blends adventure, history, and entertainment, making it an unforgettable journey from the coast to the desert.
Plan this drive from San Diego to Las Vegas for an unforgettable journey through some of Southern Californiaโs most iconic destinations, with the excitement and glamour of Las Vegas.
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