Read about 15 beautiful places to visit in the South USA that are excellent weekend getaways in the South with details on how to reach them, things to do in each area, and an overnight hotel recommendation.
👉🏼11 Best Things To Do In South Carolina – Ultimate Vacation spots in South Carolina
Best Places To Visit In South USA – Best Vacation Spots In The Southern US
The South USA boasts some of the best vacation spots in the southern states of the U.S. due to its rich tapestry of cultural heritage, warm hospitality, and diverse landscapes, including pristine beaches, historic cities, and scenic mountains, offering a multifaceted experience for travelers seeking a quintessential Southern getaway.
ALSO READ: 👉🏼Perfect East Coast Road Trip Planner USA
Charleston, South Carolina
Overnight Hotel: The Mills House Charleston.
Location: Charleston is located on the southeastern coast of South Carolina.
How to Reach: Charleston International Airport (CHS) is the primary airport. You can also reach by car via I-26 or I-526.
Charleston, SC, stands out as one of the best Places to visit in the southern States due to its rich historic charm in cobblestone streets, antebellum architecture, and vibrant plantations, coupled with its renowned Southern hospitality and diverse culinary scene.
ALSO READ: 👉🏼11 Best Beaches Near Charleston SC (Things To Do)
Things to Do:
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- Explore historic downtown and visit Rainbow Row.
- Take a carriage tour of the historic district.
- Visit Fort Sumter National Monument.
- Relax at Waterfront Park.
- Enjoy southern food on Shem Creek.
New Orleans, Louisiana
Overnight Hotel: The Roosevelt New Orleans, a Waldorf Astoria Hotel.
Location: Situated in southeastern Louisiana along the Mississippi River.
How to Reach: Louis Armstrong New Orleans International Airport (MSY) is the main airport. The city is also accessible by car via I-10.
New Orleans, Louisiana, is a top Southern destination. It is celebrated for its lively jazz-filled streets, historic French Quarter, and iconic festivals, offering a unique blend of cultural richness, culinary delights, and vibrant entertainment.
Things to Do:
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- Experience the vibrant atmosphere of the French Quarter.
- Attend a live jazz performance on Frenchmen Street.
- Explore the historic St. Louis Cemetery No. 1.
- Indulge in Creole and Cajun cuisine.
- Take a steamboat cruise on the Mississippi River.
Immerse yourself in the soulful spirit of New Orleans, where the captivating blend of music, Creole cuisine, and Mardi Gras revelry creates an unforgettable and genuinely authentic Southern experience.
Asheville, North Carolina
Overnight Hotel: The Omni Grove Park Inn.
Location: Nestled in the Blue Ridge Mountains of western North Carolina.
How to Reach: Asheville Regional Airport (AVL) serves the area. The city is accessible by car via I-40 or the scenic Blue Ridge Parkway.
Asheville stands out as one of the best vacation spots in the Southern US, nestled in the picturesque Blue Ridge Mountains, offering a perfect blend of outdoor adventure with scenic hikes, eclectic arts in the River Arts District, and a touch of grandeur at the opulent Biltmore Estate.
ALSO READ: 👉🏼11 Best Vacation Spots In North Carolina – Top Places To Visit In NC
Things to Do:
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- Visit Biltmore Estate, America’s largest home.
- Explore the vibrant arts scene in the River Arts District.
- Hike to the top of Chimney Rock for stunning views.
- Sample craft beers on the Asheville Ale Trail.
- Relax at the historic Grove Park Inn.
The city’s vibrant cultural scene, craft beer culture, and breathtaking mountain vistas make it a diverse and unforgettable destination for a Southern getaway.
Savannah, Georgia
Overnight Hotel: The Gastonian, Historic Inns Of Savannah.
Location: Located on the Georgia coast along the Savannah River.
How to Reach: Savannah/Hilton Head International Airport (SAV) is the main airport. The city is also accessible by car via I-16.
Savannah, GA, ranks among the best places to visit in South USA with its charming historic district, lined with moss-draped oaks, historic squares, and well-preserved antebellum architecture.
ALSO READ: 👉🏼11 Best Day trips from Savannah Georgia Within 2 Hours
Things to Do:
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- Stroll through Forsyth Park.
- Take a riverboat cruise on the Savannah River.
- Explore historic squares and mansions in the Historic District.
- Visit the Mercer-Williams House from “Midnight in the Garden of Good and Evil.”
- Experience a ghost tour in the evening.
The city’s rich history, southern hospitality, and enchanting riverfront contribute to its allure, creating a timeless and welcoming atmosphere for visitors.
Great Smoky Mountains National Park, Tennessee/North Carolina
Overnight Hotel: LeConte Lodge (for a unique rustic experience).
Location: Straddling the border between Tennessee and North Carolina.
How to Reach: The park is accessible by car via several entrances, including Gatlinburg, TN, and Cherokee, NC.
The Great Smoky Mountains National Park is revered as one of the best places to visit in South USA, boasting unparalleled natural beauty with mist-covered mountains, diverse wildlife, and enchanting forests.
Things to Do:
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- Hike to Clingmans Dome, the highest point in the park.
- Drive the scenic Newfound Gap Road.
- Explore Cades Cove for wildlife viewing.
- Visit the historic Roaring Fork Motor Nature Trail.
- Experience the Appalachian culture at the Mountain Farm Museum.
Visitors are drawn to its scenic drives, extensive hiking trails, and rich cultural heritage, making it a haven for outdoor enthusiasts seeking an immersive and breathtaking experience in the heart of the Appalachian Mountains.
Austin, Texas
Overnight Hotel: The Driskill, in the heart of downtown Austin.
Location: The capital city of Texas is in the central part of the state.
How to Reach: Austin-Bergstrom International Airport (AUS) is the major airport. The city is accessible by car via I-35.
Austin, Texas, earns its place among the best places to visit in South USA with its dynamic live music scene, cultural vibrancy, and laid-back atmosphere that embraces creativity and innovation.
ALSO READ: 👉🏼Perfect Texas Road Trip Itinerary (Texas Road Trip Map)
Things to Do:
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- Attend live music performances on Sixth Street.
- Explore the Texas State Capitol.
- Relax by Lady Bird Lake.
- Visit the LBJ Presidential Library.
- Enjoy the vibrant food scene, especially Tex-Mex and barbecue.
From iconic music festivals like SXSW to the scenic beauty of Lady Bird Lake, Austin offers a unique blend of arts, outdoor activities, and a diverse culinary landscape that captivates visitors seeking an authentic Texan experience.
Nashville, Tennessee
Overnight Hotel: The Hermitage Hotel.
Location: Central Tennessee along the Cumberland River.
How to Reach: Nashville International Airport (BNA) is the primary airport. The city is accessible by car via I-40.
Nashville, TN, ranks as one of the best places to visit in the South USA due to its unparalleled status as the “Music City,” featuring legendary venues like the Grand Ole Opry and vibrant honky-tonks on Broadway.
ALSO READ: 👉🏼10 Best Weekend Trips From Nashville TN (With Hotel Names)
Things to Do:
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- Experience live country music on Broadway.
- Tour the Country Music Hall of Fame.
- Visit the historic Ryman Auditorium.
- Explore the vibrant neighborhoods like 12 South and East Nashville.
Beyond its musical allure, Nashville’s rich cultural heritage, thriving food scene, and Southern hospitality contribute to its appeal, making it a must-visit destination for those seeking a quintessential Southern experience.
Myrtle Beach, South Carolina
Overnight Hotel: Marriott Myrtle Beach Resort & Spa at Grande Dunes.
Location: Along the Atlantic coast in northeastern South Carolina.
How to Reach: Myrtle Beach International Airport (MYR) is the local airport. The city is accessible by car via US-17.
Myrtle Beach, SC, emerges as a premier vacation spot in the South USA, captivating visitors with its expansive sandy beaches, a lively boardwalk, and a plethora of family-friendly attractions.
ALSO READ: 👉🏼Perfect South Carolina Road Trip Itinerary 7 Days With Map
Things to Do:
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- Relax on the sandy beaches.
- Explore the Myrtle Beach Boardwalk.
- Visit Broadway at the Beach for shopping and entertainment.
- Play golf at one of the many courses.
- Experience Ripley’s Aquarium.
The city’s sun-soaked relaxation, diverse entertainment options, and coastal charm make it an ideal destination for a memorable Southern getaway.
San Antonio, Texas
Overnight Hotel: The Menger Hotel.
Location: In south-central Texas.
How to Reach: San Antonio International Airport (SAT) is the major airport. The city is accessible by car via I-10.
San Antonio, Texas, is a top vacation spot in the South USA, renowned for its historic charm encapsulated by the Alamo, scenic River Walk, and vibrant cultural events.
Things to Do:
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- Explore the historic Alamo.
- Walk along the scenic River Walk.
- Visit the San Antonio Missions National Historical Park.
- Experience the vibrant culture of the Market Square.
- Take a boat tour along the San Antonio River.
With a rich heritage, Tex-Mex flavors, and modern attractions, San Antonio offers a diverse and captivating experience for visitors seeking a distinctive Southern adventure.
Atlanta, Georgia
Overnight Hotel: The Georgian Terrace Hotel.
Location: In northwestern Georgia.
How to Reach: Hartsfield-Jackson Atlanta International Airport (ATL) is the major airport. The city is accessible by car via I-75 and I-85.
Atlanta, Georgia, emerges as a premier vacation spot in the South USA, boasting a blend of modern sophistication with its world-class attractions like the Georgia Aquarium and historic richness showcased in the Martin Luther King Jr. National Historic Site.
ALSO READ: 👉🏼Best Road Trips From Atlanta Ga (Weekend Trips From Atlanta)
Things to Do:
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- Visit the Georgia Aquarium.
- Explore the Martin Luther King Jr. National Historic Site.
- Tour the World of Coca-Cola.
- Enjoy the view from the Atlanta SkyView Ferris Wheel.
- Walk through Piedmont Park.
With a thriving arts scene, diverse culinary offerings, and Southern hospitality, Atlanta provides visitors with a captivating and multifaceted experience.
Memphis, Tennessee
Overnight Hotel: The Peabody Memphis.
Location: In southwestern Tennessee along the Mississippi River.
How to Reach: Memphis International Airport (MEM) is the main airport. The city is accessible by car via I-40.
Memphis, Tennessee, stands as one of the top Southern cities to visit. It is celebrated for its pivotal role in music history with iconic sites like Graceland and Beale Street, offering a blend of cultural richness, soulful tunes, and delectable barbecue delights.
Things to Do:
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- Visit Graceland, Elvis Presley’s home.
- Experience the blues on Beale Street.
- Explore the National Civil Rights Museum.
- Take a riverboat cruise on the Mississippi.
- Try the famous barbecue at Central BBQ.
The city’s vibrant atmosphere, historical significance, and dedication to preserving its musical heritage make it an unforgettable destination for those seeking an authentic Southern experience.
Outer Banks, North Carolina
Overnight Hotel: Sanderling Resort.
Location: A chain of barrier islands off the coast of North Carolina.
How to Reach: Norfolk International Airport (ORF) in Virginia is the closest major airport. The Outer Banks are accessible by car via US-158.
The Outer Banks, North Carolina, ranks among the best vacation spots in the South USA, captivating visitors with its pristine beaches, historic landmarks such as the Wright Brothers Memorial, and a tranquil coastal ambiance.
Things to Do:
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- Climb the Cape Hatteras Lighthouse.
- Visit the Wright Brothers National Memorial.
- Relax on the beaches of Nags Head.
- Explore Roanoke Island.
- Take a ferry to Ocracoke Island.
With opportunities for outdoor activities, exploration of barrier islands, and the allure of maritime history, the Outer Banks offers a distinctive and rejuvenating Southern coastal retreat.
Gulf Shores, Alabama – Beach weekend getaways in the South
Overnight Hotel: The Lodge at Gulf State Park, a Hilton Hotel.
Location: On the Gulf of Mexico in southern Alabama.
How to Reach: Pensacola International Airport (PNS) in Florida is the closest major airport. Gulf Shores is accessible by car via AL-59.
Gulf Shores, Alabama, is one of the best vacation spots in the Southern US, boasting sugar-white beaches, family-friendly attractions, and a laid-back coastal atmosphere. With its Gulf Coast charm, water sports, and delectable food options, Gulf Shores provides an ideal setting for a relaxing and enjoyable Southern getaway.
Things to Do:
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- Relax on the white sandy beaches.
- Visit Gulf State Park for outdoor activities.
- Explore the Alabama Gulf Coast Zoo.
- Take a dolphin-watching cruise.
Louisville, Kentucky
Overnight Hotel: The Brown Hotel.
Location: In north-central Kentucky along the Ohio River.
How to Reach: Louisville International Airport (SDF) is the main airport. The city is accessible by car via I-65.
Louisville, Kentucky, stands out as a top vacation spot in the South USA, renowned for the exhilarating Kentucky Derby at Churchill Downs, the cultural richness of the Muhammad Ali Center, and its unique blend of bourbon heritage and urban charm.
Things to Do:
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- Attend the Kentucky Derby at Churchill Downs.
- Visit the Muhammad Ali Center.
- Explore the Louisville Mega Cavern.
- Walk across the Big Four Bridge.
- Experience the Urban Bourbon Trail.
With a vibrant arts scene, scenic parks, and the historic Big Four Bridge, Louisville offers a multifaceted and inviting experience for visitors seeking Southern hospitality and distinctive attractions.
Tampa, Florida – Southern cities to visit
Overnight Hotel: Epicurean Hotel, Autograph Collection.
Location: On the Gulf Coast of Florida.
How to Reach: Tampa International Airport (TPA) is the main airport. The city is accessible by car via I-75 and I-275.
Tampa, Florida, emerges one of the top vacation spots in the Southern US, captivating visitors with its blend of thrilling attractions like Busch Gardens, historic charm in Ybor City, and a waterfront haven along the Tampa Riverwalk.
ALSO READ: 👉🏼16 Best Weekend Getaways From Tampa, FL (Day Trips Within 3 Hours)
Things to Do:
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- Visit Busch Gardens Tampa Bay.
- Explore the historic Ybor City.
- Relax at the Tampa Riverwalk.
- Attend a game or event at Raymond James Stadium.
- Take a boat tour of Tampa Bay.
With diverse entertainment options, sporting events, and a rich cultural scene, Tampa offers a vibrant and sunny escape for those seeking an enticing Southern experience.
From the vibrant music scene in Nashville to Charleston’s coastal charm and the Smoky Mountains’ magical peaks, the South uniquely combines tradition with modernity, providing various appealing destinations that cater to different interests and preferences.
Now you know some of the best places to visit in South USA or stunning southern cities to visit with overnight stays, things to do, and how to reach.
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